Publications
Preprints
Region-specific Nucleus Accumbens Dopamine Signals Encode Distinct Aspects of Avoidance Learning. bioRxiv
2024
The Role of Dopamine in Training Automaticity. Lerner TN, Miller-Hansen AJ, and Ambrosi P. In: Vandaele, Y. (eds) Habits. Habits: Their Definition, Neurobiology, and Role in Addiction, 191-225. Springer, Cham. PDF
Dopamine across timescales and cell types: Relevance for phenotypes in Parkinson’s disease progression. Seiler JL, Zhuang X, Nelson AB, and Lerner TN. Experimental Neurology. 2024 Apr:374:114693. PubMed | PDF
Hidden variables in stress neurobiology research. Holloway AL and Lerner TN. Trends in Neurosciences. 2024 Jan;47(1):9-17. PubMed | PDF
2023
2022
Striatonigrostriatal Circuit Architecture for Disinhibition of Dopamine Signaling. Ambrosi P and Lerner TN. Cell Reports. 2022 Aug 16;40(7):111228. doi:10.1016/j.celrep.2022.111228. PubMed | PDF
Intersectional mapping of multi-transmitter neurons and other cell types in the brain. Xu J, Jo A, DeVries RP, Deniz S, Cherian S, Sunmola I, Song X, Marshall JJ, Gruner KA, Daigle TL, Contractor A, Lerner TN, Zeng H, and Zhu Y. Cell
Reports. 2022 2022 Jul 5;40(1):111036. doi: 10.1016/j.celrep.2022.111036. PubMed | PDF
Dopamine Signaling in the Dorsomedial Striatum Promotes Compulsive
Behavior. Seiler JL, Cosme CV, Sherathiya VN, Schaid MD, Bianco JM, Bridgemohan AS, and Lerner TN. Current Biology. 2022 Mar 14;32(5):1175-1188.e5 doi: 10.1016/j.cub.2022.01.055. Raw Data | PubMed | PDF
Editorial: Dopamine Neuron Diversity in Circuits and Diseases. Poulin JF, Lerner TN, and Howe MW. Frontiers in Neural Circuits. 2022 Mar 2;16:856716. doi: 10.3389/fncir.2022.856716. PubMed | PDF
2021
GuPPy, a Python toolbox for the analysis of fiber photometry data. Sherathiya VN, Schaid MD, Seiler JL, Lopez GL, and Lerner TN. Scientific Reports. 2021 Dec 20; 24212. doi: 10.1038/s41598-021-03626-9. PubMed | PDF
Dopamine, Updated: Reward Prediction Error and Beyond. Lerner TN, Holloway AL, Seiler JL. Curr Opin Neurobiol. 2021 Apr;67:123-130. doi: 10.1016/j.conb.2020.10.012. PubMed | PDF
2020
Parvalbumin+ and Npas1+ Pallidal Neurons Have Distinct Circuit Topology and Function. Pamukcu A, Cui Q, Xenias HS, Berceau BL, Augustine EC, Fan I, Chalasani S, Hantman AW, Lerner TN, Boca SM, Chan CS. J Neurosci. 2020 Oct 7;40(41):7855-7876. doi: 10.1523/JNEUROSCI.0361-20.2020. PubMed | PDF
Amygdala-Midbrain Connections Modulate Appetitive and Aversive Learning. Steinberg EE, Gore F, Heifets BD, Taylor MD, Norville ZC, Beier KT, Földy C, Lerner TN, Luo L, Deisseroth K, Malenka RC. Neuron. 2020 Jun 17;106(6):1026-1043.e9. doi: 10.1016/j.neuron.2020.03.016. PubMed | PDF
Interfacing Behavioral and Neural Circuit Models for Habit Formation. Lerner TN. J Neurosci Res. 2020 Jun;98(6):1031-1045. doi: 10.1002/jnr.24581. PubMed | PDF
2019
Neuronal Dynamics Regulating Brain and Behavioral State Transitions. Andalman AS, Burns VM, Lovett-Barron M, Broxton M, Poole B, Yang SJ, Grosenick L, Lerner TN, Chen R, Benster T, Mourrain P, Levoy M, Rajan K, Deisseroth K. Cell. 2019 May 2;177(4):970-985.e20. doi: 10.1016/j.cell.2019.02.037. PubMed | PDF
2018
2016
Nucleus accumbens D2R cells signal prior outcomes and control risky decision-making. Zalocusky KA, Ramakrishnan C, Lerner TN, Davidson TJ, Knutson B, Deisseroth K. Nature. 2016 Mar 31;531(7596):642-6. doi: 10.1038/nature17400. PubMed | PDF
Communication in Neural Circuits: Tools, Opportunities, and Challenges. Lerner TN, Ye L, Deisseroth K. Cell. 2016 Mar 10;164(6):1136-50. doi: 10.1016/j.cell.2016.02.027. PubMed | PDF
Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain. Kim CK, Yang SJ, Pichamoorthy N, Young NP, Kauvar I, Jennings JH, Lerner TN, Berndt A, Lee SY, Ramakrishnan C, Davidson TJ, Inoue M, Bito H, Deisseroth K. Nat Methods. 2016 Feb 15. doi: 10.1038/nmeth.3770. PubMed | PDF
2015
Basomedial amygdala mediates top-down control of anxiety and fear. Adhikari A*, Lerner TN*, Finkelstein J*, Pak S, Jennings JH, Davidson TJ, Ferenczi E, Gunaydin LA, Mirzabekov JJ, Ye L, Kim SY, Lei A, Deisseroth K. Nature. 2015 Nov 12;527(7577):179-85. doi: 10.1038/nature15698. *co-first authors. PubMed | PDF
Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits. Lerner TN, Shilyansky C, Davidson TJ, Evans KE, Beier KT, Zalocusky KA, Crow AK, Malenka RC, Luo L, Tomer R, Deisseroth K. Cell. 2015 Jul 30;162(3):635-47. doi: 10.1016/j.cell.2015.07.014. PubMed | PDF
2014
2012
2011
2010
2009
Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway. Quiroz C, Luján R, Uchigashima M, Simoes AP, Lerner TN, Borycz J, Kachroo A, Canas PM, Orru M, Schwarzschild MA, Rosin DL, Kreitzer AC, Cunha RA, Watanabe M, Ferré S. ScientificWorldJournal. 2009 Nov 18;9:1321-44. doi: 10.1100/tsw.2009.143. PubMed | PDF
